Birthday Celebration Puzzle Train [HINTS ADDED]

My birthday is coming in about 2 weeks (December 3rd) so, why not a celebration train? But first, you need to solve a puzzle.

This time the theme of the puzzle is a game that surprised me. I wasn't expecting much when I bought it a year ago, but I found myself addicted very soon. And it's no surprise that I'm currently addicted to the sequel.

I'm talking about Binding of Isaac series. I won't waste time explaining why those games are amazing. There's a lot of reviews out there that are far better in this matter.

The puzzle will be easier for the ones that already played one of the games. For the others, google is your friend.

Giveaways are from 0 to 3+ level and will end on my birth day, so take your time.

Go!

Hints:
Q1: His son is also called Isaac.
Q2: Uncommon red boy.
Q3: This monster punishes misbehaving children during Christmas.
Q4: The superhero holds a hammer.
Q5: Found on the Hebrew Bible.
Q6: Anarchy in papers.
Q7: Mentioned in "The Hound" and in "The Nameless City".
Q8: The book of one of the demons that possessed Emily Rose.
Q9: A board with letters and numbers.
Q10: Edmund McMillen's dead cat.