Deathtrap maybe? It's different from your usual tower defense games though.
Also, I should probably point out that I don't own the game. I just assume it's good because it's based around the tower defense mechanic from The Incredible Adventures of Van Helsing, which I liked quite bit.
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Defend Your Life it's an anatomic based tower defense
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First of all, I would like to say that I am really not a big fan of Tower Defense games.
That being said, I would recommend Winged Sakura: Mindy's Arc.
Super fast paced, RPG elements, and great art.
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Bardbarian
Commando Jack
The Culling of the Cows
Go Home Dinosaurs!
PixelJunk Monsters Ultimate
Yet Another Zombie Defense
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Sang-Froid - Tales of Werewolves is quite interesting. Not a pure tower defense, but that element is there.
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Sol Survivor
I'd recommend others but really all you need is Sol Survivor.
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Recommend me some good tower defense games folks! So far, I've been into:
Bloons TD5
Kingdom Rush
(Not too into Plants vs Zombies tho)
Anything else (preferably with multiplayer or coop)?
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