Is there any ways to use a game from a disc without using the disc?

crack.

Have you tried activating the cd-key on Uplay?

use a daemon tools maybe?

I'll check it out tomorrow. I'm sleepy. ^_^

The options are a no CD patch, drive emulation software with a copied backup of the disc or purchasing a digital copy.

For the second option, look up here to learn a little.

let put this in perspective:

stupid thread -> look for GAs -> there are none -> disappointment -> make a comment about -> you are here

Ahh No-CD cracks. It's like 2004 again!

Here's a better explanation:

Back in the day, the best option would to use a no-cd crack/patch. These are community made workarounds used mainly for pirated games. I do not know if the crack/patch itself is illegal or not. I have heard legitimate owners have used these as well (from pcgamer).

Now a days, you might be able to activate the cd key on a digital distribution service like steam, uplay, or origin, like what meirmeir said. I do not know how possible this is since I've only heard about this.

You can also rip the disc and store it as a virtual copy on your hard drive. And as ridhani1 has said, use a virtual optical drive emulator like daemons tools to "mount" the virtual copy onto a virtual drive. Ripping the disc might be hard since you'll likely have to overcome the drm protection. This also will take up a lot of space.

If you can't register the cd key onto a digital service, then I would recommend getting a no-cd crack. A good clean crack from a reliable source might be hard to find with just web searching though. No-cd patches from developers are extremely rare if existent at all.

gamecopyworld for no cd exe's . id try cloning the dvd and mounting in a virtual drive

The safest option is a mini image mouted on Daemon Tools - beause you don't change any files in your game folder, what its needed to be clear when you install some patches or want to play in Multiplayer.