I like to play it for relaxation as it is not overly complex like Cities but still has enough depth and challenge to feel great when finishing a mission.
Also install just about all the stuff from Silva: https://steamcommunity.com/profiles/76561198198801398/myworkshopfiles/?appid=464920 to have easier time on Mars with more buildings and thus options on building your colony. Thank me later, I cannot imagine playing with this because it just feels like free DLC as it is balanced and just adds options without feeling like cheating the game.