Guild Wars 2 running like crap on my GTX 1060. + other games.

It's either an issue specifically with Nvidia GPUs or some system specific conflict as I've run both Guild Wars 2 and Borderlands 2 just fine on laptops with AMD APUs previously.

Try using 1 hard drive , check all the fans for dust, check all connector's and maybe check your psu if its not giving enough power to the gpu that will cause low frame rates(could cause overheat and blow your psu) , you might need a more powerful psu , and maybe check all gpu's gold connector's again for dust or defects youll have to disconnect it from the motherboard and reconnect it , or you maybe you just need another fan under those harddiskdrive's.

My guess would be something related to Windows 10. Unfortunately a lot of games, especially older ones, seem to have issues with that OS. If you have an older OS sitting around you may want to try it to check and see if there's a difference.

Did you install the Anniversary Update?
I heard it could cause some problems with older games, because it upgrades the Windows Display Driver Model version to 2.0, so the games which just did a simple version check would be "confused", because they're searching for something (the older 1.3 version) which isn't there anymore.

Do you have the latest drivers for cpu and gpu? Clean install? Have you optimized the gfx details according to your specs and screen resolution? If you're not sure how, use nvidia geforce experience to download optimal settings for the games and see if there's any progress.

All that said, in 1080p with that card you should be able to play very high / ultra in almost any game.

"•CPU
AMD FX-8320 "

Why are people still building PC's with AMD CPU's. You'd of been better just getting a Pentium G4520.

I cant tell you anything specific sadly but it's dark side of PC gaming. I have pretty good PC as well but some games just plainly refuses to run well. Some games are badly optimized,some doesnt use your GPU at all and some just doesnt run well on specific rigs... For example i have solid 60 on Witcher 3 with Ultra settings but cant get stable on Source engine game...for some reason :D.

The problem is most likely badly optimized games especially Guild Wars ... if i remember correctly Borderlands 2 and most prob some other games as well use PhysX which runs good on Intel CPU's and purposely awful on AMD ones (as the their tech isn't open sauce). Similar issue but affecting the AMD GPU performance only > shitty NVIDIA HairWorks.

Try and disable or reduce the PhysX - that might make a great difference ...

You don't mix AMD and nVidia man.
Like DominusFerrus said, could be something related to PhysX, since nvidia and intel are BFFs and they don't play well with others, try disabling that in games that have it.

But, it could just be that the games don't go along too well with your software, rather than your hardware. I'd check forums for each one and see if other people are having problems running them in the same OS version you have.

make sure the games with problems are actually even utilizing the nvidia gpu and not just using the onboard gpu (see image)
additionally i'd mess with the physx tab as well, try changing what processor the physx is using (right below #1 arrow)

View attached image.

I played Guild Wars 2 on Windows 10 on i5 3570, 8GB RAM and GF 550Ti... It ran really fine... Also played Borderlands 2 without any problem.
In the meantime, I replaced my 550Ti for 750Ti, and Borderlands is working great (didn't try GW2, since)...

So, the problem is either faulty hardware or CPU/GF combination (or, possibly problem with drivers for 1060, but I doubt it... It's not so new any more, and we're talking about popular games)...

You shouldn't have bought AMD with GF, that is definitely true... Actually, IMO, you shouldn't have bought AMD, either way. But that's just AMD hater in me talking...

I've played GW2 for... 4865 hours and what I know is that it's very CPU reliant. The AMD FX-8320 is the cause of your poor performance. Your 1060 is powerful enough for 1080p at 60 FPS on high/medium settings.

The problem is likely that AMD tells windows it has 8 cores when it really only has 4.

This is dishonest marketing by AMD should be punished by boycotting them.

Every pair of cores shares a dispatch unit so it's really 4 cores with hyperthreading (which also sucks on Intel but they throw in extra cache and MHz to hide the failure).

For the record, Intel and nVidia also send engineers to help major engine developers solve performance issues but AMD doesn't because they spent their money on management bonuses instead of engineers for the past several years.

In the past there were patches for specific games and the Windows 7 scheduler but as AMD continued to do it many people simply quit buying them.

Do you use the energy saving setting on Windows Power Management? If so, change to the performance setting.

If my CPU is the problem, I'm seriously screwed here. I can't afford another CPU atm.

they run like crap

Like how much fps are we talking about ?

That was only a medium-grade CPU when it was released 4 years ago. Not sure why you used it in a new PC. In addition, that MB is only PCIe 2, which will limit performance in some cases.

But I'm not sure that explains GW2 being slow, given that (I think) I've run it on a slower CPU and GPU in the past.

The GPU is certainly NOT at fault here. If there's no problem with drivers, Windows, etc, then it's just the poor CPU which is holding you back. Why would you pair it with a 1060?

Your CPU is crap, either wait for Zen or buy Intel.

If this happened after the anniversary update, this just might do the trick. Turn off game DVR from your windows Xbox app.

https://www.reddit.com/r/DotA2/comments/4xu9vi/bad_fps_after_latest_win10_anniversary_update_got/

No promises tho. it fixed some of my games for me.

Maybe check the Power Management Mode in the Nvidia Control Panel > Program Settings > "Game.exe". On some games, setting it to Prefer Maximum Performance has helped me.

should have brought a RX480 :v, try reinstalling windows all together, if your previous card was AMD.

if not check your cards frequency while playing games, make sure its running at the supposed speed, and lastly try Geforce (bad)experience and "optimize" the game trough there.

First of all there's nothing inherently wrong with your CPU. The FX is still a faster processor than the majority of people on Steam have. Sure, Intels are technically better but it's not like the FX is a Pentium 4.
What is the PSU in your build?
Have you tried the GPU in a different PC or a different GPU in your PC?
Have you tried reducing the monitor settings to 720P in your games to see wether the situation improves as the GPU isn't taxed then?
Anything overclocked? Is the memory setting on automatic? Can you manually set it to 933?
Are there any case fans in your PC? Have you tried it with the side panel removed so the MB components get better cooling?
PCIe 2 or 3 doesn't make much of difference in rl.
What made me wonder is that you reported Borderlands 2 as being stuttery. The other games are CPU intensive or just crap. BL2 should be running smooth though.
Try playing with just the main system drive connected. Also disconnect as much unused stuff as possible.