What's so wrong about non-Steam DRM services?

As the title asks; what is so wrong with DRM services besides Steam? I mean, I'll be honest, I was wary of non-Steam DRM, but then I actually tried using Origin, and I had no problem. I mean, opening another window isn't as bad as you think. Now, Steam is ultimate when it comes to gaming+Socializing, but avoiding Origin/uPlay/Deusra completely just because it's not Steam just limits your options. Now, maybe not Desura, because it seems like crap anyways, but Origin and uPlay aren't any problems at all. I mean, I see people willing to spend $15 on Far Cry 3 Blood Dragon Steam keys, but if someone sells a uPlay key for $2? They won't take it. You're just wasting money. It's not that hard to open a different window.

And to the people who have never tried: Try it sometime. I mean, use your Origin keys you got from the bundle! You really have no reason not to! Now, don't go installing one of them without a game, but if you do, then go ahead! With the nVidia bundle here, Origins, Blacklist, and Black Flag will be being sold for cheap. So take this opportunity to try out other DRM services! I doubt you'll be disappointed